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OxyELITE Pro
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The OxyELITE Pro™ lineup...
Rauwolfia Canescens (Rauwolscine)
This particular compound has been suggested to block off & deactivate the Alpha-2 receptor!*
It's related to yohimbine, a compound which is often included in various thermogenic formulas because of its ability to antagonize alpha 2-adrenoceptors, allowing lipolysis itself, while also allowing lipolysis to continue from beta adrenoceptoragonism as well (11,12).*
Here's the problem: While antagonizing alpha 2-adrenoceptors is great, yohimbine unfortunately also does the same for alpha 1-adrenoceptors - and this may actually hinder lipolysis (13).*
So, on the other hand, while yohimbine may help improve lipolysis by antagonizing alpha 2-adrenoceptors, it may also prevent lipolysis from occurring by antagonizing alpha 1-adrenoceptors...*
Kind of defeats the purpose, huh? It's like robbing Peter to Pay Paul...
The end result may be only a mediocre or small effect upon fat loss, or no detectable fat loss at all, which is what has been suggested in some of the literature with yohimbine supplementation (14-17). *
Rauwolscine on the other hand, may be just as effective at antagonizing alpha 2-adrenoceptors as yohimbine, yet less potent at alpha 1-adrenoceptors (18), which may make it less likely to reduce lipolysis by inhibiting alpha 1-adrenoceptor activity when compared to yohimbine.*
Bauhinia purpurea L (Leaf & Pod [standardized for Bauhiniastatins 1-4])
This particular extract is very exciting because, due to various factors (e.g., stress, dieting, overtraining), many individuals may have impaired conversion of T4 to T3.*
We all know the thyroid plays an important role in metabolic rate.
An extract from the plant Bauhinia purpurea has been suggested in healthy adult animal models to increase T4 while also increasing T3 by an amazing 83%!* (21)
Yet another reason that increasing thyroid hormone is so important is because it's been surmised to sensitize or increase the lipolytic effects of adrenergic stimulation in fat cells* (33).
Due to the results of the studies, the authors concluded that the plant is likely increasing the conversion of peripheral T4 to T3.
Bacopa monnieri (Leaf)
This plant has also been suggested in an animal model to naturally promote thyroid hormone production.* In this case, the plant extract was suggested to increase T4 levels when compared to controls* (23).
In this case, however, since there was no increase in T3 seen, the authors concluded that the plant extract can directly stimulate the release of T4 from the thyroid gland, as opposed to Bauhinia purpurea, which increased the conversion of T4 to T3.
Geranium [Stems](extracted for 1,3-Dimethylamylamine)
Geranium has been used for centuries as a food additive and part of certain cultures' regular diets.
Cirsium Oligophyllum (Whole Plant Extract)
Our use of this plant is based upon an animal study which had suggested that compared to a control group, the extract studied was able to reduce the gain of bodyweight and fat mass and specifically seemed to target subcutaneous fat mass in rats over that of visceral fat mass!* (5)
Pharmacological studies suggest that the active constituent possesses beta adrenoceptor agonist activity and may stimulate lipolysis in subcutaneous fat cells.*
Yet another similarity that the Cirsiumoligophyllum extract shares with beta adrenoceptor agonists is that it can work synergistically with caffeine, potentially producing a more powerful lipolytic effect (5).*
In fact, the potency of caffeine & Cirsium Oligophyllum combined was nearly 10 times greater than Cirsium Oligophyllum by itself in this study.
Caffeine
Caffeine is often noted for its ability to increase resting energy expenditure, while also increasing lipolysis and lipid oxidation (6-8)...*
In addition, it is noted for its ability to increase feelings of energy, alertness, concentration and euphoric effects (9,10).*
Everyone throws caffeine in their formula...but few know why...we have a specific purpose on why we included it...
...Aside from the benefits that caffeine alone imparts, it may also provide synergistic effects when combined with other ingredients in OxyELITE Pro™...*
...In fact, in the study performed with Cirsiumoligophyllum, they surmised exactly that!*
Caffeine was suggested to provide an increase in the effectiveness of the extract at promoting lipolysis in subcutaneous fat cells (5)...*
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